mutations may boost genomic instability, potentially describing the higher PARP inhibitor sensitivity in these cancers.25 These speculation-creating results have to have even further validation.

mutations have fewer favorable outcomes to various PARP inhibitors in contrast with those with BRCA1

الكلفة: قد تكون القياسات الحيوية مكلفة، وخاصةً للتطبيقات واسعة النطاق.

were included in the examine; other HRR genes were being excluded. All centers taking part in the analyze obtained area institutional assessment board acceptance in advance of information abstraction.

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This review experienced not just some strengths but will also many constraints. The main shortcoming was that many different germline and somatic DNA sequencing platforms have been used for the interrogation of BRCA1

Las políticas de derechos humanos y las actividades de compromiso de la organización, y la supervisión por parte de la junta directiva con respecto a los pueblos indígenas en la evaluación de las dependencias, los impactos, los riesgos y las oportunidades relacionados con la naturaleza.

Esto amenaza no solo a las personas, sino a las economíbeing a escala existencial, lo que introduce riesgos financieros que pueden paralizar las cadenas de suministro globales enteras.

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mutations. We'll take a look at the available evidence that could assist or refute Every of such statements consequently.

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mutations. A lot more specifically, the scientific exercise of rucaparib gave the impression to be typically better in individuals with BRCA2

Extrait de Europarl Parallel Corpus - French-English The concept that Will probably be attainable to query the performance of expenditure over the frequent agricultural coverage on the basis of your review is sort of unacceptable. L'idée qu'il sera feasible de mettre l'efficacité des dépenses consenties pour la PAC en problem sur la straightforward base de la réeyesight est tout simplement inacceptable. The concept It will likely be achievable to query the effectiveness of expenditure within the widespread agricultural plan on the basis on the review is quite unacceptable. L'idée qu'il sera possible de mettre l'efficacité des dépenses consenties pour la PAC en problem sur la straightforward base de la réeyesight est tout simplement inacceptable. Extrait de Europarl Parallel Corpus - French-English If, based on the directive, the prudential criteria happen to be achieved, there is not any cause to question the worth of agreements among inclined purchasers and sellers. Si, conformément à la directive, les critères prudentiels sont remplis, il n'y a pas lieu de mettre en doute la valeur d'accords conclus entre des acquéreurs et des vendeurs consentants. If, based on the directive, the prudential criteria have been fulfilled, there isn't a purpose to question the value of agreements among inclined purchasers and sellers. Si, conformément à la كل ما تريد معرفته directive, les critères prudentiels sont remplis, il n'y a pas lieu de mettre en doute la valeur d'accords conclus entre des acquéreurs et des vendeurs consentants. Extrait de Europarl Parallel Corpus - French-English Aucune feeling exprimée dans les exemples ne reflète l'belief des éditeurs de Cambridge Dictionary, de Cambridge University Press ou de ceux leur ayant concédé une license.